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Executive Summary: Report No. 70 offers broad guidance to those using radionuclides for medical purposes. This Report addresses the many factors which influence the choice of the proper radio pharmaceutical drug product for the diagnosis or treatment of a specific disease or condition. The Report examines decision-making considerations in the choice of radiopharmaceutical drug products and factors relevant to the choice of instruments utilized in nuclear medicine procedures. Important parts of the Report treat radiation dose and the evaluation of radionuclide procedures in their clinical utility. The Report also includes guidelines for performing nuclear medicine procedures. One appendix sets out the guidelines for clinical evaluation of radiopharmaceutical drugs developed by the Food and Drug Administration's Radiopharmaceutical Advisory Committee. Another appendix contains estimates of absorbed dose known for radiopharmaceutical drug products.